How do you know if something has NSAIDS?
Kelly
Please note: I AM NOT A DOCTOR. If you want medical advice, talk to your doctor. Whatever I post, there is probably some surgeon or other health care provider somewhere that disagrees with me. If you want to know what your surgeon thinks, then ask him or her. Check out my blog.
NSAIDS put you at risk for ulcers. They do that to everyone, not just RNY folks. But ulcers are particularly dangerous to us. If you get an ulcer in your pouch, even a small one, since your pouch is a lot smaller than a normal stomach, it will cover a much greater percentage of your pouch. If you get an ulcer in your old stomach, docs can’t even do an endoscopy to see it. They’d have to do surgery. Also taking a medication designed to coat the stomach wouldn’t help an ulcer in the old stomach because nothing you take by mouth goes in there.
We really, really don’t want an ulcer.
NSAIDS can cause ulcers because they cause the lining of the stomach (the old stomach and the pouch) to thin out. This does NOT happen when the medication enters the pouch or touches the pouch. It happens when the medicine enters your blood stream. That’s why you can get ulcers in your old stomach. NSAIDS taken by mouth don’t touch the old stomach but can still cause ulcers there.
Any way you take an NSAID – pill, liquid, shot, IV, patch, gel – it gets into your blood stream. If it does not get into your blood stream, it will not give you any pain relief or relieve inflammation. Many docs don’t seem to understand this, though I don’t know why since they have to take pharmacology in medical school.
Some surgeons say it’s OK to take NSAIDS on a very limited basis if you really need them as long as you also take Nexium or something like that to help protect your stomach. Others say it’s never worth the risk. A few say it’s OK to take them whenever you want, but I think they are nuts. But what I really think is that we need to weigh the benefits of taking them against the risks. Is the pain of your bad back or menstrual cramps or whatever worse than the pain of an ulcer would be? If so, take the NSAID. But take it with something to protect your tummy.
Now, how likely it is that taking NSAIDS, especially rarely, will cause an ulcer, no one can say. I know people that took just one dose and got an ulcer. I know people that took them many times and had no problem. So it’s just a matter of whether or not you wanna chance it.
Kelly
Please note: I AM NOT A DOCTOR. If you want medical advice, talk to your doctor. Whatever I post, there is probably some surgeon or other health care provider somewhere that disagrees with me. If you want to know what your surgeon thinks, then ask him or her. Check out my blog.
Kelly
Please note: I AM NOT A DOCTOR. If you want medical advice, talk to your doctor. Whatever I post, there is probably some surgeon or other health care provider somewhere that disagrees with me. If you want to know what your surgeon thinks, then ask him or her. Check out my blog.
Salicylates
[edit]Propionic acid derivatives
- Ibuprofen[45]
- Dexibuprofen
- Naproxen
- Fenoprofen
- Ketoprofen
- Dexketoprofen
- Flurbiprofen
- Oxaprozin
- Loxoprofen
[edit]Acetic acid derivatives
- Indomethacin
- Sulindac
- Etodolac
- Ketorolac
- Diclofenac (Safety alert by FDA[46])
- Nabumetone (drug itself is non-acidic but the active, principal metabolite has a carboxylic acid group)
[edit]Enolic acid (Oxicam) derivatives
[edit]Fenamic acid derivatives (Fenamates )
[edit]Selective COX-2 inhibitors (Coxibs)
- Celecoxib (FDA alert[47])
- Rofecoxib (withdrawn from market[48])
- Valdecoxib (withdrawn from market[49])
- Parecoxib FDA withdrawn, licenced in the EU
- Lumiracoxib TGA cancelled registration
- Etoricoxib FDA withdrawn, licenced in the EU
- Firocoxib used in dogs and horses
[edit]Sulphonanilides
- Nimesulide (systemic preparations are banned by several countries for the potential risk of hepatotoxicity)
[edit]Others
- Licofelone acts by inhibiting LOX (lipooxygenase) & COX and hence known as 5-LOX/COX inhibitor
